Sant'Angelo a Nilo is a church in Naples, Italy. It is well known for containing the monumental tomb of Cardinal Rinaldo Brancaccio (Sepolcro del Cardinale Brancaccio) by Donatello, one of the major sculptural works in the city. Antonio Valente, the first major keyboard composer of the Neapolitan school, was organist here in 1565–80.