Anzola d'Ossola is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont, located about 110 km northeast of Turin and about 15 km northwest of Verbania. As of 31 December 2004, it had a population of 449 and an area of 13.8 km². Anzola d'Ossola borders the following municipalities: Massiola, Ornavasso, Pieve Vergonte, Premosello-Chiovenda, Valstrona.