Gignese is a comune (municipality) in the Province of Verbano-Cusio-Ossola in the Italian region Piedmont, located about 110 km northeast of Turin and about 8 km south of Verbania. As of 31 December 2004, it had a population of 913 and an area of 14.9 km². The municipality of Gignese contains the frazioni (subdivisions, mainly villages and hamlets) Alpino Cignese, Nocco, and Vezzo. Gignese borders the following municipalities: Armeno, Brovello-Carpugnino, Omegna, Stresa.