Mevo Horon (Hebrew: מְבוֹא חוֹרוֹן, lit. Horon Gateway) is an Israeli settlement and religious moshav shitufi and communal settlement in the Latrun salient. Located near Latrun and Modi'in, it falls under the jurisdiction of Mateh Binyamin Regional Council. In 2007 it had a population of 1,200.
The village was established in 1970 by members of the Ezra youth movement, and was the first village in the Mateh Binyamin council area.