The Catacomb of Priscilla on the Via Salaria in Rome, Italy, is situated in what was a quarry in Roman times. This quarry was used for Christian burials from the late 2nd century through the 4th century. Some of the walls and ceilings display fine decorations illustrating Biblical scenes. The Catacombs of Priscilla are believed to be named after Priscilla, a member of the gens Acilia and who was probably the wife of the Consul Acilius who became a Christian and was killed on the orders of Domitian. They contain a number of wall paintings of saints and early Christian symbols. Particularly notable is the "Greek Chapel" (Capella Greca), a square chamber with an arch which contains 2nd century frescoes generally interpreted to be Old and New Testament scenes, including the Fractio Panis. Above the apse is a Last Judgment. New, and somewhat controversial research has begun to suggest that the scenes traditionally interpreted as the deuterocanonical story of Susannah (Dn 13) may actually be scenes from the life of a prestigious Christian woman of the 2nd century AD. Near this are figures of the Madonna and Child and the Prophet Isaiah, also dating from the 2nd century.
The Priscilla catacombs depict the oldest Marian paintings from the middle of the second century Mary is shown with Jesus on her lap, a standing man with tunic left hand a book right hand a star over his head symbol of messiahs. Priscilla also has a depiction of the annunciation.
The catacomb of Priscilla, mentioned in all the ancient liturgical and topographic sources, has its modern entrance on the Via Salaria through the cloister of the monastery of the Benedictines of Priscilla. The Catacombs of Priscilla is divided into three principal areas: an arenarium, a cryptoportico from a large Roman villa, and an underground burial area of the noble Roman family Acilius Glabrio.